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Dr. Rodier's Research Perspectives: Alzheimer's

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Meow $P1,

Dr. Rodier's "Research Perspectives" 

Thoughts from a leading integrative physician and medical insider

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Featured Article for Discussion

Toward prevention of Alzheimer’s disease: potential nutraceutical strategies for suppressing the production of amyloid beta peptides” Medical Hypotheses 2006; 67, Issue 4:682-697

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If we live to age 85, our chances of getting “All-timer’s” disease are about 50%. I don’t know about you, but that worries me. I don’t want to end up losing my mind, at least no more than I occasionally do already.

What can we do to reduce our chances of developing this disease? Many ask if drugs really help with dementia. I’m afraid that recent research is cause for pessimism. Sorry.

According to a 2006 article, Role of cholinesterase inhibitors in dementia care needs rethinking in the British Medical Journal, three authors, all psychiatrists, conclude that for dementia:

“…the only currently licensed medicines for a cruel illness have turned out to be of marginal benefit—from statistical, clinical, and public health viewpoints.”

However, according to my featured article, "Toward prevention of Alzheimer's disease," we need to “change our oil,” and I don’t mean at the Jiffy Lube.

Eighty percent of our brains are made up of fats, or phospholipids (I know, it seems that we all know people whose brains are fully 100% fat). Anyway, we can support “regeneration” of our brains with good dietary oils, particularly docosahexaenoic acid, or DHA, an omega 3 fatty acid.

But it’s not a matter of just adding “good” oils. We need to quit eating the bad ones, namely trans-hydrogenated fats, and we also need to reduce our intake of saturated fats dramatically.

Researchers are now beginning to understand that so-called “degenerative” diseases -- like Alzheimer’s and Parkinson’s -- are not entirely due to degenerative problems but are due also to a failure of the brain to “regenerate.”

The notion that our brain is cast in stone and can only degenerate with age is an old paradigm. We need to think “regeneration” -- with nutrition being key to success.

In addition to DHA, my featured article mentions: policosanol, beta carotene, hops extracts, minerals (low salt, high potassium), folate, flavonol-rich cocoa, chromium picolinate, cinnamon extracts, vitamin D, genistein, and sesamin.

Of the many nutrients mentioned, the most essential in my opinion, are DHA and vitamin D.

Our Health Co-op’s Multi-Vites, Sam’s Advanced Antioxidant Plus D, and new Liquid Calcium all have Vitamin D3, a form of D which is getting plenty of good press in medical journals.

Given the research, I would like to see everyone getting at least 1000 IU of supplemental Vitamin D3 each day, since most people I test are critically low in vitamin D.

By the way, vitamin D is not formed in your skin if you merely sit by a window. You must be outside to benefit from solar production of vitamin D in your skin (ideally as naked as possible, which I don’t recommend if you have touchy neighbors or if it’s cold outside)!

Finally, my featured article does leave out a couple of very important things for brain health.

1. The article neglects to address the damaging effects of insulin on our brains (there is a small mention of chromium picolinate and cinnamon extracts as “aids for insulin sensitivity,” but that’s hardly enough). Overwhelming evidence ("Insulin Effects Weigh Heavy on the Brain" Friedrich J. of American Medical Association 2006; 296: 1717-1718.) indicates that sweets basically “caramelize” your noodle. If you want to protect your brain, you need to get serious about getting off refined sugars!

 

2. While the article makes passing note of the value of exercise in preventing or slowing Alzheimer’s, the authors neglected to include the importance of learning something new (and doing so often), like learning to play a musical instrument, speak a new language, compete in a complex game, etc. If you haven’t learned something new recently, take it on as a New Year’s challenge!

In summary: Keep your brain nourished. Keep your insulin in check. And, keep your brain active!

Dr. Rodier practices integrative medicine at the Pioneer Health Clinic just outside Salt Lake City, UT. He's an adjunct professor for the University of Utah's School of Medicine. Dr. Rodier offers nutritional consultations via phone. Please inquire for details. To contact Dr. Rodier, write to hugo@ourhealthcoop.com, or for more information, visit his web site at: www.hugorodier.com.

You can read more from Dr. Rodier in his blog:

Braindroppings: Cutting-edge musings on health & healing


New & Improved Liquid Calcium in Stock!

Our Liquid Calcium passed testing and is back in stock. We've improved our formula to now include vitamin D3 (100 IU) and boron (1mg) all in one easy-to-swallow softgel! Stock up for the winter here.

We added Vitamin D after many requests and based on current research, which all points to the importance of increasing vitamin D intake for optimum health.

Many of our members are aware of the relationship between high vitamin D levels and reduced incidence of Multiple Sclerosis.

But fair members, there's more. Did you know these vitamin D facts?

1. According to research by a leading nutritional epidemiologist, women in their mid-80's who received 800 IU of supplemental vitamin D performed better -- in leg strength and experienced half the number of falls of their calcium-only peers! 

2. According to The Journal of Clinical Endocrinology & Metabolism, sunlight at northern latitudes is not equally effective in promoting vitamin D3 synthesis in the skin. Beware in Boston, Boise, and Bangor!

3. According to The American Journal of Clinical Nutrition, obese people obtain a minimum of 50% less bioavailable vitamin D from exposure to sunlight.

4. According to the Vitamin D Council, vitamin D deficiency plays a role in causing 17 varieties of cancer, heart disease, stroke, hypertension, autoimmune diseases, diabetes, depression, chronic pain, osteoarthritis, osteoporosis, muscle weakness, muscle wasting, birth defects and periodontal disease.

So, forget the outdated idea that 400 IU of vitamin D is plenty. The latest research shows the importance of getting more vitamin D -- between 1000 - 2000 IU daily -- for healthy bones and a whole lot more.

Our improved Liquid Calcium, now with magnesium, D3 (the more bioavailable form), and boron will help you increase your intake of vitamin D.

For example, taking three Liquid Calcium softgels daily provides 300 IU of highly bioavailable vitamin D3.  Add Multi-Vites, Sam's Plus D, and a little sunshine and you're in business.  ^..^


Health in the News

Meanwhile, the humans keep making noises about "2007 is gonna be a good year."  Makes my tail twitch.  Based on what?  According to whom?  Totally unscientific.  Pfffsst.  This kat?  I'm just happy knowing today is good.  Hope yours is too!  ^..^

Still purringly yours,

Guido

Guido Housemouser
Chief Kat and Community Manager
Our Health Co-op

4188 Westroads Drive, Unit 123

Riviera Beach, FL 33407

 

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