Genetics research is
everywhere these days. Good genes. Bad genes. Cancer
genes. Obesity genes. Chances are you've heard at least
something about your genes lately.
It's much less likely,
however, that you've heard much about your genes' boss
-- the epigenome. Since, the epigenome's
management skills can make or break your health, despite
how good or bad your given genes are, this kat thought
you should know more.
The Epigenome: Master
of Cells, Master of Fate?
Epigenome literally means
"on top of the genome" and refers to all the factors
that control how genes are expressed -- and even
whether a particular gene ever gets expressed.
Take recent research on
identical twins, for example.
Identical twins come from
the same egg, have the same genetic code, and are thus
completely genetically identical. However, when it comes
to health problems later in life, what affects one twin
often doesn't affect the other, even with diseases that
have a reputation for being genetic, like cancer.
Researchers got curious
and discovered a way to measure which genes were "on"
and "off."
Genes from 40 pairs of
identical twins, ages 3 to 74, were overlapped to
measure discrepancy. Genes of younger twins overlapped
almost completely, showing highly similar DNA strands.
However, genes of older twins had far fewer overlaps and
thus far fewer similarities.
This means that
lifestyle and environmental influences -- like diet,
exercise, smoking, drinking, stress, toxins, etc. --
all influence how the epigenome manages gene expression.
"People think there is
nothing you can do (about your disease risk)," said
researcher Rod Dashwood of Oregon State University (yes,
home of The Linus Pauling Institute, for our Dr. Pauling
fans out there).
But, fair members, genes
do not spell destiny so much as tendency.
Diet's Vital Role in
Gene Expression
For decades, studies have been associating diet with
disease risk. Now, research on the epigenome may be
revealing the mechanism at play.
Dashwood's work indicates that many whole foods —
including broccoli sprouts, onions, garlic, radishes,
wasabi, daikon, horseradish and wheat bran — may "switch
off" genes that lead to degenerative
diseases, such as cancer, heart disease, stroke and even
aging. Conversely bad diets can work against your genes.
Researchers at Georgetown
University discovered an unhealthy balance of omega-6
fatty acids (all-too-common in the American diet) may
indirectly turn off genes that impact normal cell
life-cycles. Cells can then proliferate and lead
to tumors, which are essentially a bundle of multiplying
cells gone wild.
Managing Gene Expression – Healthy Basics
I know that you all know the basics – more whole
foods, more exercise, less stress. I hate to be a nag,
but you humans require so many repetitions sometimes, so
here’s a reminder about cellular health. ^..^
Remember Dr. Rodier’s central focus on helping cells
stop “TOILing” by addressing toxicity, oxidation,
inflammation, and lack of mitochondrial energy?
While most of our members are savvy on antioxidants
to fight free radicals and omega-3 fatty acids (fish
oil) to fight inflammation, cellular detoxification is
still relatively new to many.
Detoxifying products you
may want to consider include:
Milk Thistle,
Constant Health, and
Alpha Lipoic Acid.
Visit the Co-op on Facebook!
It's finally happened. After several emails
encouraging your favorite feline (ahem!) to get a Facebook account,
we've set up an
Our Health Co-op page as well as a personal account for
yours truly,
Guido Housemouser.
If you're not too familiar with Facebook, you can "Like"
the Co'op's page (meaning you'll get updates in your News Feed whenever we post
anything) by clicking the "Like" button at the top of our Facebook page. You can
also friend moi, just as you would friend any human.
So fair members, friend us, tell your friends about us, check for updates. You never
know, you may just see coupons and other specials exclusive to Facebook users.
^..^